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EMD-52961

Single-particle
2.71 Å
EMD-52961
3D View Gallery
Deposition: 26/02/2025
Map released: 01/10/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52961
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9q9j summary report (pdf.gz) Map and 9q9j FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Mre11-Rad50-Nbs1 (MRN) complex bound to DNA and telomeric factor TRF2 fragment (438-542)

EMD-52961

Single-particle
2.71 Å
EMD-52961
3D View Gallery
Deposition: 26/02/2025
Map released: 01/10/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: MRN-TRF2(438-542)-DNA complex
Fitted models: 9q9j

Deposition Authors: Cui HJ, Lammens K, Hopfner KP, Fan YL, Kuybu F
Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.
Fan Y, Kuybu F, Cui H, Lammens K, Chen JX, Kugler M, Jung C, Hopfner KP
(2025) Nat Commun , 16 , 8320 - 8320
PUBMED: 40968163
DOI: doi:10.1038/s41467-025-64082-x
ISSN: 2041-1723
Grant Support: