Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-52863
HSV-2 postfusion glycoprotein B
EMD-52863
Single-particle2.21 Å
Deposition: 20/02/2025Map released: 03/09/2025
Last modified: 22/10/2025
Sample Organism:
Human herpesvirus 2 strain 333
Sample: Human herpesvirus 2 strain 333
Fitted models: 9ih8
Deposition Authors: Vollmer B
,
Mulvaney T ,
Ebel H ,
Nentwig J ,
Gruenewald K
Sample: Human herpesvirus 2 strain 333
Fitted models: 9ih8
Deposition Authors: Vollmer B
,
Mulvaney T ,
Ebel H ,
Nentwig J ,
Gruenewald K
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2.
Vollmer B ,
Ebel H ,
Rees R,
Nentwig J ,
Mulvaney T ,
Schunemann J,
Krull J,
Topf M ,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
,
Ebel H ,
Rees R,
Nentwig J ,
Mulvaney T ,
Schunemann J,
Krull J,
Topf M ,
Gorlich D,
Grunewald K
(2025) Nature , 646 , 433 - 441
Grant Support:
- German Research Foundation (DFG): INST 152/772-1 (Germany)
- German Research Foundation (DFG): 152/774-1 (Germany)
- German Research Foundation (DFG): 152/776-1 (Germany)
- German Federal Ministry for Education and Research: ASPIRE project (Germany)
- Wellcome Trust: 209250/Z/17/Z (United Kingdom)