EMD-52815

Single-particle
2.54 Å
EMD-52815
3D View Gallery
Deposition: 14/02/2025
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52815

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ibx summary report (pdf.gz) Map-9ibx FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Chimeric mitochondrial DNA polymerase gamma ternary complex (mAhB) in replication conformer

EMD-52815

Single-particle
2.54 Å
EMD-52815
3D View Gallery
Deposition: 14/02/2025
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens, synthetic construct
Sample: Chimeric mitochondrial DNA polymerase gamma ternary complex (mAhB) in replication conformer
Fitted models: 9ibx

Deposition Authors: Valenzuela S , Falkenberg M
Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Corra S, Zuppardo A , Valenzuela S , Jenninger L, Cerutti R, Sillamaa S , Hoberg E, Johansson KAS , Rovsnik U , Volta S, Silva-Pinheiro P , Davis H, Trifunovic A , Minczuk M , Gustafsson CM , Suomalainen A , Zeviani M, Macao B , Zhu X , Falkenberg M , Viscomi C
(2025) Nat Commun , 16 , 4782 - 4782
PUBMED: 40404629
DOI: doi:10.1038/s41467-025-60059-y
ISSN: 2041-1723
Grant Support: