EMD-52458

Single-particle
3.7 Å
EMD-52458
3D View Gallery
Deposition: 07/01/2025
Map released: 12/02/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52458
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9hxa summary report (pdf.gz) Map and 9hxa FULL report (pdf.gz)
EMICSS annotations (xml)

In vitro grown K58N Alpha-Synuclein Fibrils

EMD-52458

Single-particle
3.7 Å
EMD-52458
3D View Gallery
Deposition: 07/01/2025
Map released: 12/02/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha-Synuclein K58N
Fitted models: 9hxa

Deposition Authors: Sicking K, Al-Azzani M , Outeiro TF, Fernandez-Busnadiego R
A novel alpha-synuclein K58N missense variant in a patient with Parkinson's disease.
Al-Azzani M , Weber S, Ramalingam N, Ramon M, Shvachiy L, Mestre G, Zech M, Sicking K, Ibanez de Opakua A, Jayanthi V, Amaral L, Agarwal A, Chandran A, Chaves SR , Winkelmann J, Trenkwalder C, Schwager M, Pauli S, Dettmer U, Fernandez CO, Lautenschlager J, Zweckstetter M, Busnadiego RF, Mollenhauer B, Outeiro TF
(2025) Medrxiv
PUBMED: 39990587
DOI: doi:10.1101/2025.02.07.25321793
ISSN: 0000-0000