EMD-52297

Single-particle
3.4 Å
EMD-52297
3D View Gallery
Deposition: 09/12/2024
Map released: 03/09/2025
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52297

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hms summary report (pdf.gz) Map-9hms FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human separase bound to SCC1 (310-550 aa) and SA2

EMD-52297

Single-particle
3.4 Å
EMD-52297
3D View Gallery
Deposition: 09/12/2024
Map released: 03/09/2025
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human separase bound to SCC1 (310-550 aa) and SA2
Fitted models: 9hms

Deposition Authors: Yu J , Schmidt S , Botto M , Boland A
Substrate recognition by human separase.
Yu J , Schmidt S , Botto M , Lee K, Ghent CM, Goodfried JM, Howe A, O'Reilly FJ, Morgan DO , Boland A
(2025) Sci Adv , 11 , eady9807 - eady9807
PUBMED: 41223273
DOI: doi:10.1126/sciadv.ady9807
ISSN: 2375-2548