EMD-52247

Single-particle
2.5 Å
EMD-52247
3D View Gallery
Deposition: 04/12/2024
Map released: 15/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52247

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hl9 summary report (pdf.gz) Map-9hl9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH P/E-site tRNA AND mRNA : LM14Cs1H3 sKO STRAIN

EMD-52247

Single-particle
2.5 Å
EMD-52247
3D View Gallery
Deposition: 04/12/2024
Map released: 15/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Leishmania major strain Friedlin
Sample: 80S RIBOSOME WITH P/E-site tRNA AND mRNA
Fitted models: 9hl9

Deposition Authors: Rajan KS , Yonath A
p -Alkoxy-Substituted Anisomycins with Potent Anti-Trypanosomiasis Activity and Expanded Modes of Action.
Bora Bhowal K , Nguyen AMT, Ibarra-Meneses AV, Brito Lira A, Rajan KS , Castano JD , Beaudry F, Bashan A, Fernandez-Prada C , Olivier M, Yonath A, Lubell WD
(2025) J Med Chem , 68 , 20264 - 20282
PUBMED: 40980996
DOI: doi:10.1021/acs.jmedchem.5c01291
ISSN: 0022-2623
ASTM: JMCMAR
Grant Support: