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EMD-52226
Structure of Zincore (SEPHS1:QRICH1) binding to ZFP91 on DNA
EMD-52226
Single-particle3.26 Å
Deposition: 02/12/2024Map released: 09/07/2025
Last modified: 16/07/2025
Sample Organism:
Homo sapiens
Sample: Zincore
Fitted models: 9hjt
Deposition Authors: Borza R
,
Perrakis A
Sample: Zincore
Fitted models: 9hjt
Deposition Authors: Borza R
,
Perrakis A
Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.
Bianchi D ,
Borza R ,
De Zan E ,
Huelsz-Prince G,
Gregoricchio S ,
Dekker M,
Fish A ,
Mazouzi A ,
Kroese LJ,
Linder S ,
Hernandez-Quiles M,
Vermeulen M ,
Celie PHN ,
Krimpenfort P,
Song JY ,
Zwart W,
Wessels L ,
Nijman SMB ,
Perrakis A ,
Brummelkamp TR
(2025) Science , 389 , eadv2861 - eadv2861
,
Borza R ,
De Zan E ,
Huelsz-Prince G,
Gregoricchio S ,
Dekker M,
Fish A ,
Mazouzi A ,
Kroese LJ,
Linder S ,
Hernandez-Quiles M,
Vermeulen M ,
Celie PHN ,
Krimpenfort P,
Song JY ,
Zwart W,
Wessels L ,
Nijman SMB ,
Perrakis A ,
Brummelkamp TR
(2025) Science , 389 , eadv2861 - eadv2861
Grant Support:
- Oncode Institute: (Netherlands)