EMD-52213

Single-particle
3.35 Å
EMD-52213
3D View Gallery
Deposition: 28/11/2024
Map released: 30/07/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52213

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hjd summary report (pdf.gz) Map-9hjd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of domperidone-bound human SLC19A3 in inward-open state

EMD-52213

Single-particle
3.35 Å
EMD-52213
3D View Gallery
Deposition: 28/11/2024
Map released: 30/07/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: hSLC19A3:Nb3.3:domperidone
Fitted models: 9hjd

Deposition Authors: Gabriel F , Loew C
Structure-based discovery of thiamine uptake inhibitors.
Gabriel F , Windshugel B , Low C
(2025) Br.J.Pharmacol. , 182 , 5611 - 5626
PUBMED: 40702645
DOI: doi:10.1111/bph.70133
ISSN: 0007-1188
ASTM: BJPCBH
Grant Support: