EMD-52050

Single-particle
2.78 Å
EMD-52050
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Deposition: 11/11/2024
Map released: 17/09/2025
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52050
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9hco summary report (pdf.gz) Map and 9hco FULL report (pdf.gz)
EMICSS annotations (xml)

Outward-open structure of human serotonin transporter bound to vilazodone

EMD-52050

Single-particle
2.78 Å
EMD-52050
3D View Gallery
Deposition: 11/11/2024
Map released: 17/09/2025
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Complex of the Serotonin Transporter with the antidepressant vilazodone
Fitted models: 9hco

Deposition Authors: Kalenderoglou IE , Tillmann P, Loland CJ
Structural basis of vilazodone dual binding mode to the serotonin transporter.
Kalenderoglou IE , Nygaard A , Vogt CD, Turaev A, Pape T , Adams NBP, Newman AH, Loland CJ
(2025) Nat Commun , 16 , 10119 - 10119
PUBMED: 41253806
DOI: doi:10.1038/s41467-025-65202-3
ISSN: 2041-1723