EMD-52050

Single-particle
2.78 Å
EMD-52050
3D View Gallery
Deposition: 11/11/2024
Map released: 17/09/2025
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52050

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hco summary report (pdf.gz) Map-9hco FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Outward-open structure of human serotonin transporter bound to vilazodone

EMD-52050

Single-particle
2.78 Å
EMD-52050
3D View Gallery
Deposition: 11/11/2024
Map released: 17/09/2025
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Complex of the Serotonin Transporter with the antidepressant vilazodone
Fitted models: 9hco

Deposition Authors: Kalenderoglou IE , Tillmann P, Loland CJ
Structural basis of vilazodone dual binding mode to the serotonin transporter.
Kalenderoglou IE , Nygaard A , Vogt CD, Turaev A, Pape T , Adams NBP, Newman AH, Loland CJ
(2025) Nat Commun , 16 , 10119 - 10119
PUBMED: 41253806
DOI: doi:10.1038/s41467-025-65202-3
ISSN: 2041-1723