Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-51963

Single-particle
3.6 Å
EMD-51963 Deposition: 30/10/2024
Map released: 04/12/2024
Last modified: 04/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51963

Cryo-EM structure of the human GABAA receptor alpha1 subunit in complex with the assembly factor NACHO/TMEM35A

EMD-51963

Single-particle
3.6 Å
EMD-51963 Deposition: 30/10/2024
Map released: 04/12/2024
Last modified: 04/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of Gamma-aminobutyric acid receptor subunit alpha-1 with assembly factor NACHO/TMEM35A
Fitted models: 9h9e

Deposition Authors: Hooda Y , Sente A , Judy RM , Smalinskaite L , Peak-Chew S, Naydenova K , Malinauskas T , Hardwick SW , Chirgadze DY , Aricescu AR , Hegde RS
Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels.
PUBMED: 39553992
DOI: doi:10.1101/2024.10.28.620708
ISSN: 2692-8205