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EMD-51516

Single-particle
2.61 Å
EMD-51516
3D View Gallery
Deposition: 10/09/2024
Map released: 09/07/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51516
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9gr0 summary report (pdf.gz) Map and 9gr0 FULL report (pdf.gz)
EMICSS annotations (xml)

Interaction with AK2A links AIFM1 to cellular energy metabolism. The cryo-EM structure of dimeric AIFM1 bound by AK2A.

EMD-51516

Single-particle
2.61 Å
EMD-51516
3D View Gallery
Deposition: 10/09/2024
Map released: 09/07/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimeric Complex of Apoptosis inducing factor mitochondrial 1 (AIFM1) bound by adenylate kinase 2 isoform A (AK2A)
Fitted models: 9gr0

Deposition Authors: Rothemann RA, Pavlenko EA, Gerlich S, Grobushkin P, Mostert S, Stobbe D, Racho J, Stillger K, Lapacz K, Petrungaro C, Dengjel J , Neundorf I, Bano D , Mondal M, Weiss K, Ehninger D, Nguyen THD , Poepsel SP, Riemer J
Interaction with AK2A links AIFM1 to cellular energy metabolism.
Rothemann RA, Pavlenko E , Mondal M, Gerlich S, Grobushkin P, Mostert S, Racho J, Weiss K, Stobbe D, Stillger K, Lapacz K, Salscheider SL, Petrungaro C, Ehninger D, Nguyen THD , Dengjel J , Neundorf I, Bano D , Poepsel S, Riemer J
(2025) Mol Cell , 85 , 2550
PUBMED: 40578348
DOI: doi:10.1016/j.molcel.2025.05.036
ISSN: 1097-2765
ASTM: MOCEFL