EMD-51515
Interaction with AK2A links AIFM1 to cellular energy metabolism. The cryo-EM structure of dimeric AIFM1 engaged to MIA40.
EMD-51515
Single-particle2.36 Å
Deposition: 10/09/2024Map released: 09/07/2025
Last modified: 16/07/2025
Sample Organism:
Homo sapiens
Sample: Complex of Apoptosis inducing factor mitochondrial 1 (AIFM1) with the Mitochondrial intermembrane space import and assembly protein 40 (MIA40)
Fitted models: 9gqz
Deposition Authors: Rothemann RA, Pavlenko EA, Gerlich S, Grobushkin P, Mostert S, Stobbe D, Racho J, Stillger K, Lapacz K, Petrungaro C, Dengjel J
,
Neundorf I,
Bano D ,
Mondal M,
Weiss K,
Ehninger D,
Nguyen THD ,
Poepsel SP,
Riemer J
Sample: Complex of Apoptosis inducing factor mitochondrial 1 (AIFM1) with the Mitochondrial intermembrane space import and assembly protein 40 (MIA40)
Fitted models: 9gqz
Deposition Authors: Rothemann RA, Pavlenko EA, Gerlich S, Grobushkin P, Mostert S, Stobbe D, Racho J, Stillger K, Lapacz K, Petrungaro C, Dengjel J
,
Neundorf I,
Bano D ,
Mondal M,
Weiss K,
Ehninger D,
Nguyen THD ,
Poepsel SP,
Riemer J
Interaction with AK2A links AIFM1 to cellular energy metabolism.
Rothemann RA,
Pavlenko E ,
Mondal M,
Gerlich S,
Grobushkin P,
Mostert S,
Racho J,
Weiss K,
Stobbe D,
Stillger K,
Lapacz K,
Salscheider SL,
Petrungaro C,
Ehninger D,
Nguyen THD ,
Dengjel J ,
Neundorf I,
Bano D ,
Poepsel S,
Riemer J
(2025) Mol Cell , 85 , 2550
,
Mondal M,
Gerlich S,
Grobushkin P,
Mostert S,
Racho J,
Weiss K,
Stobbe D,
Stillger K,
Lapacz K,
Salscheider SL,
Petrungaro C,
Ehninger D,
Nguyen THD ,
Dengjel J ,
Neundorf I,
Bano D ,
Poepsel S,
Riemer J
(2025) Mol Cell , 85 , 2550
Grant Support:
- German Research Foundation (DFG): RI2150/5-1 (Germany)
- German Research Foundation (DFG): SPP2453 (Germany)
- German Research Foundation (DFG): RTG2550/1 (Germany)
- German Research Foundation (DFG): 455 SFB1430 (Germany)