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EMD-51502

Single-particle
3.35 Å
EMD-51502
3D View Gallery
Deposition: 06/09/2024
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51502
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9gp7 summary report (pdf.gz) Map and 9gp7 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo EM structure of the E307T mutant of the human P2X4 receptor in complex with the anthraquinone derivative PSB-0704

EMD-51502

Single-particle
3.35 Å
EMD-51502
3D View Gallery
Deposition: 06/09/2024
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human P2X4 receptor
Fitted models: 9gp7

Deposition Authors: Nagel J, Vaaen V, Torp J, Geyer M, Claff T, Hagelueken G, Mueller CE

Discovery of an allosteric P2X receptor binding site for anthraquinones by a chimeric approach combined with computational studies, bump-and-hole mutagenesis, and cryo-electron microscopy
Nagel J, Weinhausen S, Namasivayam V, Baqi Y, Al Musawi HAM, Abdelrahman A, Vaassen V, Schlegel J, Taplick L, Torp J, Kubicek J, Maertens B, Geyer M, Claff T, Hagelueken G, Mueller CE
To Be Published