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EMD-51497
Cryo-EM structure of the multiple peptide resistance factor (MprF) from Pseudomonas aeruginosa bound to a synthetic nanobody (Sb29)
EMD-51497
Single-particle3.28 Å
Deposition: 05/09/2024Map released: 12/03/2025
Last modified: 23/04/2025
Sample Organism:
Pseudomonas aeruginosa PAO1,
synthetic construct
Sample: Complex of PaMprF with Sybody29 in Saposin A-protein nanoparticles
Fitted models: 9goe
Deposition Authors: Hankins MTK
,
Parrag M
,
Garaeva AA
,
Earp JC
,
Seeger MA
,
Stansfeld PJ
,
Bublitz M
Sample: Complex of PaMprF with Sybody29 in Saposin A-protein nanoparticles
Fitted models: 9goe
Deposition Authors: Hankins MTK
,
Parrag M
,
Garaeva AA
,
Earp JC
,
Seeger MA
,
Stansfeld PJ
,
Bublitz M
MprF from Pseudomonas aeruginosa is a promiscuous lipid scramblase with broad substrate specificity.
Hankins MTK
,
Parrag M
,
Garaeva AA
,
Earp JC
,
Seeger MA
,
Stansfeld PJ
,
Bublitz M
(2025) Sci Adv , 11 , eads9135 - eads9135
,
Parrag M
,
Garaeva AA
,
Earp JC
,
Seeger MA
,
Stansfeld PJ
,
Bublitz M
(2025) Sci Adv , 11 , eads9135 - eads9135
Grant Support:
- Wellcome Trust: 102161/Z/13/Z (United Kingdom)
