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EMD-51477
Microtubule-associated Kif5B IAK tail mutant bound to ADP
EMD-51477
Single-particle2.9 Å
Deposition: 03/09/2024Map released: 20/11/2024
Last modified: 16/07/2025
Sample Organism:
Sus scrofa,
Homo sapiens
Sample: 13pf microtubule bound to Kif5bMoNeXXX in the presence of ADP
Fitted models: 9gnq
Deposition Authors: Atherton J
,
Chegkazi MS,
Steiner RA
Sample: 13pf microtubule bound to Kif5bMoNeXXX in the presence of ADP
Fitted models: 9gnq
Deposition Authors: Atherton J
,
Chegkazi MS,
Steiner RA
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail.
Atherton J
,
Chegkazi MS,
Leusciatti M,
Di Palma M
,
Peirano E
,
Pozzer LS
,
Meli MVA,
Pasqualato S
,
Foran T,
Morra G
,
Steiner RA
(2025) Nat Commun , 16 , 6214 - 6214
,
Chegkazi MS,
Leusciatti M,
Di Palma M
,
Peirano E
,
Pozzer LS
,
Meli MVA,
Pasqualato S
,
Foran T,
Morra G
,
Steiner RA
(2025) Nat Commun , 16 , 6214 - 6214
Grant Support:
- Wellcome Trust: 206175/Z/17/Z (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/V006568/1 (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/S000828/1 (United Kingdom)
