EMD-51330

Single-particle
2.65 Å
EMD-51330
3D View Gallery
Deposition: 13/08/2024
Map released: 16/04/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51330
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ggf summary report (pdf.gz) Map and 9ggf FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of WT human mitochondrial DNA polymerase gamma

EMD-51330

Single-particle
2.65 Å
EMD-51330
3D View Gallery
Deposition: 13/08/2024
Map released: 16/04/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Structure of WT human mitochondrial DNA polymerase gamma
Fitted models: 9ggf

Deposition Authors: Valenzuela S , Falkenberg M
Small molecules restore mutant mitochondrial DNA polymerase activity.
Valenzuela S , Zhu X, Macao B, Stamgren M, Geukens C, Charifson PS, Kern G, Hoberg E, Jenninger L, Gruszczyk AV , Lee S, Johansson KAS , Miralles Fuste J , Shi Y, Kerns SJ, Arabanian L, Martinez Botella G, Ekstrom S, Green J , Griffin AM, Pardo-Hernandez C, Keating TA , Kuppers-Munther B, Larsson NG , Phan C, Posse V , Jones JE, Xie X, Giroux S , Gustafsson CM , Falkenberg M
(2025) Nature , 642 , 501 - 507
PUBMED: 40205042
DOI: doi:10.1038/s41586-025-08856-9
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: