EMD-51277
Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with ToxR and TcpP transcription factors and a toxT promoter DNA fragment
EMD-51277
Composite mapSingle-particle
2.9 Å
Deposition: 06/08/2024Map released: 17/12/2025
Last modified: 28/01/2026
Sample Organism:
Vibrio cholerae O395,
Vibrio cholerae O1 biovar El Tor str. N16961
Sample: Virulent transcription complex #5
Fitted models: 9gds
Deposition Authors: Alcaide-Jimenez A
,
Baudin F
,
Canals A
,
Machon C
,
Murciano B
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Krukonis ES
,
Muller CW
,
Coll M
Sample: Virulent transcription complex #5
Fitted models: 9gds
Deposition Authors: Alcaide-Jimenez A
,
Baudin F
,
Canals A
,
Machon C
,
Murciano B
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Krukonis ES
,
Muller CW
,
Coll M
Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Alcaide-Jimenez A
,
Canals A
,
Baudin F
,
Machon C
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Murciano B
,
Mohammad AA,
Rowse MJ,
Ferracciolo JM,
Krukonis ES
,
Muller CW
,
Coll M
(2026) Sci Adv , 12 , eadx9680 - eadx9680
,
Canals A
,
Baudin F
,
Machon C
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Murciano B
,
Mohammad AA,
Rowse MJ,
Ferracciolo JM,
Krukonis ES
,
Muller CW
,
Coll M
(2026) Sci Adv , 12 , eadx9680 - eadx9680
Grant Support:
