EMD-51183
Structure of human PHLPP2 in conformation 2
EMD-51183
Single-particle5.8 Å
Deposition: 28/07/2024Map released: 26/03/2025
Last modified: 16/04/2025
Sample Organism:
Homo sapiens
Sample: recombinant human PHLPP2
Deposition Authors: Siess K, Grishkovskaya I
,
Haselbach D ,
Leonard TA
Sample: recombinant human PHLPP2
Deposition Authors: Siess K, Grishkovskaya I
,
Haselbach D ,
Leonard TA
PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor.
Husremovic T,
Meier V,
Piech L,
Siess KM,
Antonioli S,
Grishkovskaya I ,
Kircheva N,
Angelova SE ,
Wenzl K,
Brandstatter A ,
Veis J,
Miocic-Stosic F,
Anrather D ,
Hartl M ,
Truebestein L,
Cerron-Alvan LM,
Leeb M,
Zagrovic B ,
Hann S ,
Bock C ,
Ogris E ,
Dudev T ,
Irwin NAT,
Haselbach D ,
Leonard TA
(2025) PNAS , 122 , e2417218122 - e2417218122
,
Kircheva N,
Angelova SE ,
Wenzl K,
Brandstatter A ,
Veis J,
Miocic-Stosic F,
Anrather D ,
Hartl M ,
Truebestein L,
Cerron-Alvan LM,
Leeb M,
Zagrovic B ,
Hann S ,
Bock C ,
Ogris E ,
Dudev T ,
Irwin NAT,
Haselbach D ,
Leonard TA
(2025) PNAS , 122 , e2417218122 - e2417218122
Grant Support:
- Austrian Science Fund: P33066 (Austria)
- Austrian Science Fund: P36212 (Austria)
- Austrian Science Fund: W1261 (Austria)
- Diamond Light Source: BI25222-3 (United Kingdom)