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EMD-51076
TRPC5 in complex with photoswitch Z-AzHC
EMD-51076
Single-particle2.9 Å
Deposition: 16/07/2024Map released: 30/07/2025
Last modified: 30/07/2025
Sample Organism:
Homo sapiens
Sample: Homotetrameric TRPC5 ion channel in complex with a efficacy photo-switch, agonist state.
Fitted models: 9g50
Deposition Authors: Porav SA
,
Bon R,
Muench S
Sample: Homotetrameric TRPC5 ion channel in complex with a efficacy photo-switch, agonist state.
Fitted models: 9g50
Deposition Authors: Porav SA
,
Bon R,
Muench S
Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues
Muller M,
Niemeyer K,
Ojha NK
,
Porav SA
,
Vinayagam D
,
Urban N
,
Buchau F,
Oleinikov K,
Makke M,
Bauer CC
,
Johnson AJ
,
Muench SP
,
Zufall F
,
Bruns D,
Schwarz Y,
Raunser S
,
Leinders-Zufall T
,
Bon RS
,
Schaefe M
,
Thorn-Seshold O
To Be Published
,
Porav SA
,
Vinayagam D
,
Urban N
,
Buchau F,
Oleinikov K,
Makke M,
Bauer CC
,
Johnson AJ
,
Muench SP
,
Zufall F
,
Bruns D,
Schwarz Y,
Raunser S
,
Leinders-Zufall T
,
Bon RS
,
Schaefe M
,
Thorn-Seshold O
To Be Published
Grant Support:
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/P020208/1 (United Kingdom)
