Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-51074

Single-particle
2.6 Å
EMD-51074
3D View Gallery
Deposition: 16/07/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51074
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9g4y summary report (pdf.gz) Map and 9g4y FULL report (pdf.gz)
EMICSS annotations (xml)

TRPC5 in complex with photoswitch E-AzHC

EMD-51074

Single-particle
2.6 Å
EMD-51074
3D View Gallery
Deposition: 16/07/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric TRPC5 ion channel in complex with a efficacy photo-switch, antagonist state.
Fitted models: 9g4y

Deposition Authors: Porav SA , Bon R, Muench S

Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues
Muller M, Niemeyer K, Ojha NK , Porav SA , Vinayagam D , Urban N , Buchau F, Oleinikov K, Makke M, Bauer CC , Johnson AJ , Muench SP , Zufall F , Bruns D, Schwarz Y, Raunser S , Leinders-Zufall T , Bon RS , Schaefe M , Thorn-Seshold O
To Be Published