EMD-51074

Single-particle
2.6 Å
EMD-51074
3D View Gallery
Deposition: 16/07/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51074

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9g4y summary report (pdf.gz) Map-9g4y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TRPC5 in complex with photoswitch E-AzHC

EMD-51074

Single-particle
2.6 Å
EMD-51074
3D View Gallery
Deposition: 16/07/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric TRPC5 ion channel in complex with a efficacy photo-switch, antagonist state.
Fitted models: 9g4y

Deposition Authors: Porav SA , Bon R, Muench S

Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues
Muller M, Niemeyer K, Ojha NK , Porav SA , Vinayagam D , Urban N , Buchau F, Oleinikov K, Makke M, Bauer CC , Johnson AJ , Muench SP , Zufall F , Bruns D, Schwarz Y, Raunser S , Leinders-Zufall T , Bon RS , Schaefe M , Thorn-Seshold O
To Be Published