Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-50990

Single-particle
2.35 Å
EMD-50990 Deposition: 11/07/2024
Map released: 23/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50990

Cryo-EM map of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA

EMD-50990

Single-particle
2.35 Å
EMD-50990 Deposition: 11/07/2024
Map released: 23/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Candida albicans, Candida albicans SC5314
Sample: Candida albicans ribosome in complex with initiator fMet-tRNA, mRNA, and GEN+MFQ
Fitted models: 9g30

Deposition Authors: Kolosova O , Zgadzay Y , Jenner LB, Guskov A , Yusupov M
Mechanism of read-through enhancement by aminoglycosides and mefloquine.
Kolosova O , Zgadzay Y , Stetsenko A , Sukhinina AP , Atamas A , Validov S, Rogachev A , Usachev K , Jenner L , Dmitriev SE , Yusupova G , Guskov A , Yusupov M
(2025) PNAS , 122 , e2420261122 - e2420261122
PUBMED: 40273100
DOI: doi:10.1073/pnas.2420261122
ISSN: 1091-6490
ASTM: PNASA6