EMD-50962

Single-particle
3.4 Å
EMD-50962
3D View Gallery
Deposition: 10/07/2024
Map released: 18/06/2025
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50962

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9g23 summary report (pdf.gz) Map-9g23 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Yeast RNA polymerase I elongation complex stalled by an apurinic site bound to nucleotide analog AMPCPP at A-site

EMD-50962

Single-particle
3.4 Å
EMD-50962
3D View Gallery
Deposition: 10/07/2024
Map released: 18/06/2025
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: RNA polymerase I and DNA and RNA
Fitted models: 9g23

Deposition Authors: Santos-Aledo A , Plaza-Pegueroles A, Ruiz FM , Fernandez-Tornero C
Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Santos-Aledo A , Plaza-Pegueroles A, Sanz-Murillo M, Ruiz FM , Hou P , Xu J , Gil-Carton D , Wang D , Fernandez-Tornero C
(2025) Nat Commun , 16 , 5254 - 5254
PUBMED: 40480971
DOI: doi:10.1038/s41467-025-60536-4
ISSN: 2041-1723