EMD-50925

Single-particle
3.0 Å
EMD-50925
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Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50925
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Local refinement of the RNF213 ATPase domain in the structure of human RNF213 bound to the secreted effector IpaH2.5 from Shigella flexneri

EMD-50925

Single-particle
3.0 Å
EMD-50925
3D View Gallery
Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo
Sample: E3 ligase RNF213, bound to the secreted effector IpaH2.5 from Shigella flexneri

Deposition Authors: Naydenova K, Randow F
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213.
Naydenova K, Boyle KB, Pathe C, Pothukuchi P, Crespillo-Casado A, Scharte F , Hammoudi PM, Otten EG , Alto NM , Randow F
(2025) Nat Struct Mol Biol , 32 , 1741 - 1751
PUBMED: 40205224
DOI: doi:10.1038/s41594-025-01530-8
ISSN: 1545-9985
Grant Support: