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EMD-50914

Composite map
Single-particle
3.4 Å
EMD-50914
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Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50914
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9g09 summary report (pdf.gz) Map and 9g09 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human RNF213 bound to the secreted effector IpaH2.5 from Shigella flexneri

EMD-50914

Composite map
Single-particle
3.4 Å
EMD-50914
3D View Gallery
Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Shigella flexneri 5a str. M90T
Sample: E3 ligase RNF213, bound to the secreted effector IpaH2.5 from Shigella flexneri
Fitted models: 9g09

Deposition Authors: Naydenova K, Randow F
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213.
Naydenova K, Boyle KB, Pathe C, Pothukuchi P, Crespillo-Casado A, Scharte F , Hammoudi PM, Otten EG , Alto NM , Randow F
(2025) Nat Struct Mol Biol , 32 , 1741 - 1751
PUBMED: 40205224
DOI: doi:10.1038/s41594-025-01530-8
ISSN: 1545-9985
Grant Support: