EMD-50913

Single-particle
3.3 Å
EMD-50913
3D View Gallery
Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50913

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9g08 summary report (pdf.gz) Map-9g08 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of human RNF213 bound to the secreted effector IpaH1.4 from Shigella flexneri

EMD-50913

Single-particle
3.3 Å
EMD-50913
3D View Gallery
Deposition: 07/07/2024
Map released: 16/04/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Shigella flexneri 5a str. M90T
Sample: E3 ligase RNF213, bound to the secreted effector IpaH1.4 from Shigella flexneri
Fitted models: 9g08

Deposition Authors: Naydenova K, Randow F
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213.
Naydenova K, Boyle KB, Pathe C, Pothukuchi P, Crespillo-Casado A, Scharte F , Hammoudi PM, Otten EG , Alto NM , Randow F
(2025) Nat Struct Mol Biol , 32 , 1741 - 1751
PUBMED: 40205224
DOI: doi:10.1038/s41594-025-01530-8
ISSN: 1545-9985
Grant Support: