EMD-50894
Proton conductance by human uncoupling protein 1 is inhibited by both purine and pyrimidine nucleotides
EMD-50894
Single-particle3.03 Å
Deposition: 05/07/2024Map released: 05/03/2025
Last modified: 02/07/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: UCP1 bound to UTP and in complex with two Pro-macrobodies
Fitted models: 9fzq
Deposition Authors: Jones SA
,
Sowton AP ,
Lacabanne D ,
King MS ,
Palmer SM ,
Zogg T ,
Pardon E ,
Steyaert J ,
Ruprecht JJ ,
Kunji ERS
Sample: UCP1 bound to UTP and in complex with two Pro-macrobodies
Fitted models: 9fzq
Deposition Authors: Jones SA
,
Sowton AP ,
Lacabanne D ,
King MS ,
Palmer SM ,
Zogg T ,
Pardon E ,
Steyaert J ,
Ruprecht JJ ,
Kunji ERS
Proton conductance by human uncoupling protein 1 is inhibited by purine and pyrimidine nucleotides.
Jones SA ,
Sowton AP ,
Lacabanne D ,
King MS ,
Palmer SM ,
Zogg T ,
Pardon E ,
Steyaert J ,
Ruprecht JJ ,
Kunji ERS
(2025) EMBO J , 44 , 2353 - 2365
,
Sowton AP ,
Lacabanne D ,
King MS ,
Palmer SM ,
Zogg T ,
Pardon E ,
Steyaert J ,
Ruprecht JJ ,
Kunji ERS
(2025) EMBO J , 44 , 2353 - 2365
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UU_00028/2 (United Kingdom)
- European Union (EU): Instruct-ERIC/ESFRI (European Union)
- Research Foundation - Flanders (FWO): (Belgium)