Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-50637

Single-particle
2.9 Å
EMD-50637
3D View Gallery
Deposition: 13/06/2024
Map released: 03/07/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50637
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9fp6 summary report (pdf.gz) Map and 9fp6 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the NbNRC2 hexameric resistosome

EMD-50637

Single-particle
2.9 Å
EMD-50637
3D View Gallery
Deposition: 13/06/2024
Map released: 03/07/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Nicotiana benthamiana
Sample: NbNRC2a
Fitted models: 9fp6

Deposition Authors: Webster MW , Madhuprakash J , Kamoun S
A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity.
Madhuprakash J , Toghani A , Contreras MP , Posbeyikian A , Richardson J , Kourelis J , Bozkurt TO , Webster MW , Kamoun S
(2024) Sci Adv , 10 , eadr2594 - eadr2594
PUBMED: 39504373
DOI: doi:10.1126/sciadv.adr2594
ISSN: 2375-2548