EMD-50336

Single-particle
3.1 Å
EMD-50336
3D View Gallery
Deposition: 17/05/2024
Map released: 28/05/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50336

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9fe1 summary report (pdf.gz) Map-9fe1 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the ternary DARPin NY_1/HLA-A0201/NY-ESO1 complex.

EMD-50336

Single-particle
3.1 Å
EMD-50336
3D View Gallery
Deposition: 17/05/2024
Map released: 28/05/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Ternary complex formed between the DARPin NY_1 and HLA-A0201/hb2m/NY-ESO1_157-165(9V)
Fitted models: 9fe1

Deposition Authors: Schulte T, Wallden K, Carroni M, Sandalova T, Walser M, Mueller S, Venetz N, Achour A
Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes.
Venetz-Arenas N, Schulte T, Muller S, Wallden K, Fischer S, Resink T, Kadri N, Paladino M, Pina N, Radom F, Villemagne D, Bruckmaier S, Cornelius A, Hospodarsch T, Alici E, Ljunggren HG, Chambers BJ, Han X, Sun R, Carroni M, Levitsky V, Sandalova T, Walser M, Achour A
(2025) iScience , 28 , 113926 - 113926
PUBMED: 41321628
DOI: doi:10.1016/j.isci.2025.113926
ISSN: 2589-0042
Grant Support: