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EMD-50336

Single-particle
3.1 Å
EMD-50336
3D View Gallery
Deposition: 17/05/2024
Map released: 28/05/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50336
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9fe1 summary report (pdf.gz) Map and 9fe1 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the ternary DARPin NY_1/HLA-A0201/NY-ESO1 complex.

EMD-50336

Single-particle
3.1 Å
EMD-50336
3D View Gallery
Deposition: 17/05/2024
Map released: 28/05/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Ternary complex formed between the DARPin NY_1 and HLA-A0201/hb2m/NY-ESO1_157-165(9V)
Fitted models: 9fe1

Deposition Authors: Schulte T, Wallden K, Carroni M, Sandalova T, Walser M, Mueller S, Venetz N, Achour A
Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes.
Venetz-Arenas N, Schulte T, Muller S, Wallden K, Fischer S, Resink T, Kadri N, Paladino M, Pina N, Radom F, Villemagne D, Bruckmaier S, Cornelius A, Hospodarsch T, Alici E, Ljunggren HG, Chambers BJ, Han X, Sun R, Carroni M, Levitsky V, Sandalova T, Walser M, Achour A
(2025) iScience , 28 , 113926 - 113926
PUBMED: 41321628
DOI: doi:10.1016/j.isci.2025.113926
ISSN: 2589-0042
Grant Support: