EMD-50333
Betaglycan Orphan Domain (ratBGo) in complex with TGF-b1 and extracellular domain of TGFBRII
EMD-50333
Single-particle3.4 Å
Deposition: 17/05/2024Map released: 12/03/2025
Last modified: 12/03/2025
Sample Organism:
Homo sapiens,
Rattus norvegicus
Sample: Ternary complex of Rat Betaglycan Orphan Domain (ratBGo) with TGF-B1 and extracellular domains of TGFBRII
Fitted models: 9fdy
Deposition Authors: Wieteska L
,
Cherepanov P ,
Punch E,
Hinck AP ,
Hill CS
Sample: Ternary complex of Rat Betaglycan Orphan Domain (ratBGo) with TGF-B1 and extracellular domains of TGFBRII
Fitted models: 9fdy
Deposition Authors: Wieteska L
,
Cherepanov P ,
Punch E,
Hinck AP ,
Hill CS
Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Wieteska L ,
Taylor AB ,
Punch E,
Coleman JA,
Conway IO,
Lin YF ,
Byeon CH ,
Hinck CS,
Krzysiak T,
Ishima R,
Lopez-Casillas F ,
Cherepanov P ,
Bernard DJ ,
Hill CS ,
Hinck AP
(2025) Nat Commun , 16 , 1778 - 1778
,
Taylor AB ,
Punch E,
Coleman JA,
Conway IO,
Lin YF ,
Byeon CH ,
Hinck CS,
Krzysiak T,
Ishima R,
Lopez-Casillas F ,
Cherepanov P ,
Bernard DJ ,
Hill CS ,
Hinck AP
(2025) Nat Commun , 16 , 1778 - 1778
Grant Support:
- H2020 Marie Curie Actions of the European Commission: 893196 (European Union)
- The Francis Crick Institute: CC2021 (United Kingdom)
- The Francis Crick Institute: CC2058 (United Kingdom)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM058670 (United States)