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EMD-50273
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
EMD-50273
Single-particle2.6 Å
Deposition: 10/05/2024Map released: 02/07/2025
Last modified: 02/07/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
Fitted models: 9faj
Deposition Authors: Kasaragod VB
,
Aricescu AR
Sample: CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
Fitted models: 9faj
Deposition Authors: Kasaragod VB
,
Aricescu AR
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/15 (United Kingdom)
- European Molecular Biology Organization (EMBO): ALTF137-2019 (European Union)
- H2020 Marie Curie Actions of the European Commission: GABAARComp-897707 (European Union)
- Medical Research Council (MRC, United Kingdom): MR/L009609/1 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_EX_MR/T046279/1 (United Kingdom)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 1R01-GM135550 (United States)
- National Science Foundation (NSF, United States): NeuroNex 2014862 (United States)
