EMD-49972

Single-particle
2.5 Å
EMD-49972
3D View Gallery
Deposition: 02/04/2025
Map released: 25/02/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49972

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o0g summary report (pdf.gz) Map-9o0g FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of M. mazei topoisomerase VI(A-E342Q)-minicircle DNA complex in cleavage state

EMD-49972

Single-particle
2.5 Å
EMD-49972
3D View Gallery
Deposition: 02/04/2025
Map released: 25/02/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: unidentified, Methanosarcina mazei Go1
Sample: Topoisomerase VI heterotetramer (A2B2) bound to minicircle DNA and ADPNP
Fitted models: 9o0g

Deposition Authors: Richman DE , Berger JM
Supercoiled DNA recognition and cleavage control in topoisomerase VI.
Richman DE , Wendorff TJ, Rashid F , Beck C, Yan Q, Johnson HR , Eckerty RA, Fogg JM, Baker ML , Zechiedrich L , Berger JM
(2026) Nat Commun , 17
PUBMED: 41698922
DOI: doi:10.1038/s41467-026-69491-0
ISSN: 2041-1723