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EMD-49876

Single-particle
3.2 Å
EMD-49876
3D View Gallery
Deposition: 22/03/2025
Map released: 18/06/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49876
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nwe summary report (pdf.gz) Map and 9nwe FULL report (pdf.gz)
EMICSS annotations (xml)

E3 ligase UBR4-KCMF1-calmodulin complex

EMD-49876

Single-particle
3.2 Å
EMD-49876
3D View Gallery
Deposition: 22/03/2025
Map released: 18/06/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human E3 ubiquitin ligase UBR4-KCMF1-calmodulin complex (Silencing Factor of ISR, SiFI)
Fitted models: 9nwe

Deposition Authors: Yang Z , Rape MP
Molecular basis of SIFI activity in the integrated stress response.
Yang Z , Haakonsen DL, Heider M, Witus SR, Zelter A , Beschauner T, MacCoss MJ , Rape M
(2025) Nature , 643 , 1117 - 1126
PUBMED: 40328314
DOI: doi:10.1038/s41586-025-09074-z
ISSN: 1476-4687
ASTM: NATUAS