EMD-49646

Single-particle
2.97 Å
EMD-49646
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Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49646
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Magnesium ions-bound closed-state cryo-EM structure of human TRPV6 in cNW11 nanodiscs

EMD-49646

Single-particle
2.97 Å
EMD-49646
3D View Gallery
Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: sample 1
Fitted models: 9nq9

Deposition Authors: Neuberger A, Sobolevsky AI
The locking mechanism of human TRPV6 inhibition by intracellular magnesium.
Neuberger A, Shalygin A, Veretenenko II, Trofimov YA, Gudermann T, Chubanov V, Efremov RG, Sobolevsky AI
(2025) Nat Commun , 16 , 9826 - 9826
PUBMED: 41198662
DOI: doi:10.1038/s41467-025-65919-1
ISSN: 2041-1723