Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-49626

Single-particle
3.4 Å
EMD-49626 Deposition: 11/03/2025
Map released: 19/03/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49626

Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA

EMD-49626

Single-particle
3.4 Å
EMD-49626 Deposition: 11/03/2025
Map released: 19/03/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycolicibacterium smegmatis MC2 155, Mycolicibacterium smegmatis, synthetic construct
Sample: AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA
Fitted models: 9np6

Deposition Authors: Warren GM, De la Cruz MJ, Goldgur Y, Shuman S

Structure of an initiation complex mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals locl melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor