EMD-49521

Single-particle
3.53 Å
EMD-49521
3D View Gallery
Deposition: 03/03/2025
Map released: 07/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49521

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nlp summary report (pdf.gz) Map-9nlp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HIV-1 Reverse Transcriptase with New Non-Nucleoside Reverse Transcriptase Inhibitor 12126065

EMD-49521

Single-particle
3.53 Å
EMD-49521
3D View Gallery
Deposition: 03/03/2025
Map released: 07/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: HIV-1 06TG.HT008
Sample: HIV-1 reverse transcriptase with novel inhibitor
Fitted models: 9nlp

Deposition Authors: Young MA, Lane TR , Raman R, Nelson JAE, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Rees SD , Quinnell D, Chang G, Ekins S
Cryo-EM Structure of HIV-1 Reverse Transcriptase with N -Phenyl-1-(phenylsulfonyl)-1 H -1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside Inhibitor.
Young MA, Lane TR , Raman R, Nelson JAE, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Rees SD , Quinnell D, Makarov V, Chang G, Ekins S
(2025) Acs Infect Dis. , 11 , 1257 - 1267
PUBMED: 40304150
DOI: doi:10.1021/acsinfecdis.5c00189
ISSN: 2373-8227
Grant Support: