EMD-49306

Single-particle
3.2 Å
EMD-49306
3D View Gallery
Deposition: 19/02/2025
Map released: 13/08/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49306

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nee summary report (pdf.gz) Map-9nee FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The flexible portion of Cryo-EM structure of Herpesvirus Helicase-Primase complex with Pritelivir

EMD-49306

Single-particle
3.2 Å
EMD-49306
3D View Gallery
Deposition: 19/02/2025
Map released: 13/08/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Herpesviridae
Sample: The ternary complex of HSV-1 UL8/UL52/UL5 helicase-primase complex
Fitted models: 9nee

Deposition Authors: Yao Q , Yu X, Baker D, Jensen G
Structural and mechanistic insights into herpesvirus helicase-primase and its therapeutic inhibitors.
Yao Q , Mercier A , Nayak A, May L, Ho PY, Lewis-Ballester A, Nair V , Sapre A, Aeschbacher T, Mukherjee J, Richards C , Mateo R, Cho A, Lansdon E , Yu X
(2025) Nat Microbiol , 10 , 3191 - 3201
PUBMED: 41188384
DOI: doi:10.1038/s41564-025-02168-4
ISSN: 2058-5276
Grant Support: