EMD-49261

Single-particle
3.4 Å
EMD-49261
3D View Gallery
Deposition: 16/02/2025
Map released: 18/02/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49261

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nco summary report (pdf.gz) Map-9nco FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

IN-ML-15 bound to IGF1Rzip

EMD-49261

Single-particle
3.4 Å
EMD-49261
3D View Gallery
Deposition: 16/02/2025
Map released: 18/02/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: IN-ML-15 IGF1Rzip complex
Fitted models: 9nco

Deposition Authors: Kirk NS

Neuroprotective potential of an engineered hormone with dual insulin and IGF-1 receptor activity
Selicharova I, Kirk NS, Lubos M, Kertisova A, Mitrova K, Zakova L, Chrudinova M, Brezinova J, Harant K, Voldrich J, Panikova T, Torres-Aleman I, Huffman D, Jiracek J
To Be Published
Grant Support: