EMD-49206

Single-particle
3.85 Å
EMD-49206
3D View Gallery
Deposition: 13/02/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49206

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nb1 summary report (pdf.gz) Map-9nb1 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CRYO-EM STRUCTURE OF human U7 SNRNP WITH MUTANT LSM11 that disrupts contacts with CPSF73

EMD-49206

Single-particle
3.85 Å
EMD-49206
3D View Gallery
Deposition: 13/02/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Trichoplusia ni, Mus musculus
Sample: Full U7 snRNP complex assembled with LSm11 helix mutant
Fitted models: 9nb1

Deposition Authors: Desotell A, Tong L
An N-terminal helix of Lsm11 stabilizes CPSF73 in U7 snRNP for histone pre-mRNA 3'-end processing.
Desotell A, Marzluff WF , Dominski Z, Tong L
(2026) Nucleic Acids Res , 54
PUBMED: 41495886
DOI: doi:10.1093/nar/gkaf1442
ISSN: 1362-4962
ASTM: NARHAD