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EMD-49184

Single-particle
2.54 Å
EMD-49184
3D View Gallery
Deposition: 11/02/2025
Map released: 23/07/2025
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49184
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nab summary report (pdf.gz) Map and 9nab FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the alpha5beta1 integrin headpiece with OS2966 Fab

EMD-49184

Single-particle
2.54 Å
EMD-49184
3D View Gallery
Deposition: 11/02/2025
Map released: 23/07/2025
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Human integrin alpha5beta1 headpiece in complex with the Fab fragment of OS2966
Fitted models: 9nab

Deposition Authors: Wang L, Zhang C
ITGB1 Regulates Triple-Negative Breast Cancer Development by Modulating the Tumor Microenvironment.
Song N , Chen S, Wang L, Dang J, Cao X, Singh S, Yang L, Wang J, Rosen ST, Wang Y, Chen CD, Zhang C, Feng M
(2026) Adv Sci , e13672 - e13672
PUBMED: 41632816
DOI: doi:10.1002/advs.202513672
ISSN: 2198-3844
Grant Support:
  • National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 5R35GM128641 (United States)
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