EMD-49130

Single-particle
3.22 Å
EMD-49130
3D View Gallery
Deposition: 08/02/2025
Map released: 04/02/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49130

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n8j summary report (pdf.gz) Map-9n8j FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs

EMD-49130

Single-particle
3.22 Å
EMD-49130
3D View Gallery
Deposition: 08/02/2025
Map released: 04/02/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus, Plasmodium falciparum
Sample: Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by four potent mAbs
Fitted models: 9n8j

Deposition Authors: Hailemariam S, Ivanochko D, Julien JP
A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity.
Ivanochko D, Miura K , Hailemariam S, Ravichandran R, Song Y, Huang WC, Stoter R, Teelen K, van Gemert GJ, Leaf EM, Chan S, Men C, Semesi A, Shiu C, MacGill RS , Long CA , Jore MM , King NP , Lovell JF , Julien JP
(2026) Nat Commun , 17
PUBMED: 41580424
DOI: doi:10.1038/s41467-026-68761-1
ISSN: 2041-1723