EMD-48770

Single-particle
3.16 Å
EMD-48770
3D View Gallery
Deposition: 23/01/2025
Map released: 10/09/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48770

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 Half-map 3 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mzw summary report (pdf.gz) Map-9mzw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

PP2A Holoenzyme with B55 subunit

EMD-48770

Single-particle
3.16 Å
EMD-48770
3D View Gallery
Deposition: 23/01/2025
Map released: 10/09/2025
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PP2A Holoenzyme with B55 subunit
Fitted models: 9mzw

Deposition Authors: Shi S, Li X, Alderman C, Huang W , Foulon N , Rossi J, Cui S, Taylor D, Ford HL, Zhao R
Cryo-EM structures reveal the PP2A-B55 alpha and Eya3 interaction that can be disrupted by a peptide inhibitor.
Shi S, Li X, Alderman C, Wick L , Huang W , Foulon N , Zhang L, Rossi J, Hu W, Cui S, Zheng H, Taylor DJ, Ford HL, Zhao R
(2025) J Biol Chem , 301 , 110287 - 110287
PUBMED: 40414499
DOI: doi:10.1016/j.jbc.2025.110287
ISSN: 1083-351X
ASTM: JBCHA3