Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-48724

Single-particle
9.8 Å
EMD-48724
3D View Gallery
Deposition: 21/01/2025
Map released: 02/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48724
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9mxz summary report (pdf.gz) Map and 9mxz FULL report (pdf.gz)
EMICSS annotations (xml)

Lecithin:Cholesterol Acyltransferase Bound to Apolipoprotein A-I dimer in HDL

EMD-48724

Single-particle
9.8 Å
EMD-48724
3D View Gallery
Deposition: 21/01/2025
Map released: 02/04/2025
Last modified: 07/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of 2 Lecithin:Cholesterol Acyltransferase molecules bound to Apolipoprotein dimer in HDL
Fitted models: 9mxz

Deposition Authors: Coleman B, Bedi S , Hill JH, Morris J, Manthei KA, Hart RC, He Y, Shah AS , Jerome WG , Vaisar T , Bornfeldt KE, Song H, Segrest JP, Heinecke JW, Aller SG, Tesmer JJG, Davidson S
Lecithin:cholesterol acyltransferase binds a discontinuous binding site on adjacent apolipoprotein A-I belts in HDL.
Coleman B, Bedi S , Hill JH, Morris J, Manthei KA, Hart RC, He Y, Shah AS , Jerome WG , Vaisar T , Bornfeldt KE, Song H, Segrest JP, Heinecke JW, Aller SG, Tesmer JJG, Davidson WS
(2025) J Lipid Res , 66 , 100786 - 100786
PUBMED: 40147634
DOI: doi:10.1016/j.jlr.2025.100786
ISSN: 0022-2275
ASTM: JLPRAW