EMD-48668

Single-particle
3.43 Å
EMD-48668
3D View Gallery
Deposition: 15/01/2025
Map released: 25/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48668

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mvs summary report (pdf.gz) Map-9mvs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Activated Leptotrichia buccalis (Lbu) CRISPR-Cas13a bound to AI-designed anti-CRISPR AIcrVIA1

EMD-48668

Single-particle
3.43 Å
EMD-48668
3D View Gallery
Deposition: 15/01/2025
Map released: 25/02/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Leptotrichia buccalis
Sample: Activated Leptotrichia buccalis (Lbu) CRISPR-Cas13a bound to AI-designed anti-CRISPR AIcrVIA1
Fitted models: 9mvs

Deposition Authors: Taveneau C , Knott GJ
De novo design of potent CRISPR-Cas13 inhibitors.
Taveneau C , Chai HX, D'Silva J, Bamert RS, Chen H, Hayes BK , Calvert RW , Purcell J, Curwen DJ , Munder F , Martin LL , Barr JJ , Rosenbluh J, Fareh M, Grinter R , Knott GJ
(2026) Nat Chem Biol , 22 , 1342 - 1350
PUBMED: 41588195
DOI: doi:10.1038/s41589-025-02136-3
ISSN: 1552-4469
Grant Support: