EMD-48606

Single-particle
2.66 Å
EMD-48606
3D View Gallery
Deposition: 11/01/2025
Map released: 19/11/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48606

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mte summary report (pdf.gz) Map-9mte FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of extracellular domain of human HER2 complexed with two nano-bodies 27A05 and 47D05

EMD-48606

Single-particle
2.66 Å
EMD-48606
3D View Gallery
Deposition: 11/01/2025
Map released: 19/11/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Lama glama, Homo sapiens
Sample: CryoEM structure of extracellular domain of human HER2 complexed with two nano-bodies 27A05 and 47D05
Fitted models: 9mte

Deposition Authors: Bruch EM , Rak A
TPP-45142-an Anti-HER2 T-cell Engager-Designed for Selective HER2-Low Cancer Immunotherapy.
De Tavernier E , Kim PS , Bruch EM , Cortez-Retamozo VF , Timmerman L , Flynn AL , Van Overbeke W , Tirode F , Cintra Barbosa-Lorenzi V , Piepenhagen P , Dinh-Le T , Luna E , Li A , Baker A , Rak A , Pao LI , Vintem APB
(2026) Mol.Cancer Ther. , 25 , 541 - 555
PUBMED: 41504346
DOI: doi:10.1158/1535-7163.MCT-25-0654
ISSN: 1538-8514
Grant Support: