EMD-48563

Single-particle
2.44 Å
EMD-48563
3D View Gallery
Deposition: 08/01/2025
Map released: 29/10/2025
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48563

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mrt summary report (pdf.gz) Map-9mrt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human TRPM4 channel in a calcium and PI(4,5)P2 bound open state

EMD-48563

Single-particle
2.44 Å
EMD-48563
3D View Gallery
Deposition: 08/01/2025
Map released: 29/10/2025
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human TRPM4
Fitted models: 9mrt

Deposition Authors: Teixeira-Duarte CM, Jiang Y
Structural landscape of activation, desensitization and inhibition in the human TRPM4 channel.
Teixeira-Duarte CM, Zeng W, Jiang Y
(2026) Nat Struct Mol Biol , 33 , 43 - 52
PUBMED: 41174278
DOI: doi:10.1038/s41594-025-01705-3
ISSN: 1545-9985