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EMD-48492

Single-particle
3.6 Å
EMD-48492
3D View Gallery
Deposition: 29/12/2024
Map released: 08/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48492
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

The methyltransferases-focused cryo-EM map of nucleosome-bound DNA methyltransferases DNMT3A2 and DNMT3L

EMD-48492

Single-particle
3.6 Å
EMD-48492
3D View Gallery
Deposition: 29/12/2024
Map released: 08/10/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample: human DNA methyltransferase 3A2 and 3L complex

Deposition Authors: Yan Y , Zhou XE , Xu TH
Mechanisms of DNMT3A-3L-mediated de novo DNA methylation on chromatin.
Yan Y , Zhou XE , Thomas SL, Liu M, Lai GQ, Worden EJ, Jones PA, Xu TH
(2025) Nat Struct Mol Biol
PUBMED: 41174279
DOI: doi:10.1038/s41594-025-01704-4
ISSN: 1545-9985