EMD-48457

Single-particle
2.7 Å
EMD-48457
3D View Gallery
Deposition: 26/12/2024
Map released: 21/05/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48457

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9moe summary report (pdf.gz) Map-9moe FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318

EMD-48457

Single-particle
2.7 Å
EMD-48457
3D View Gallery
Deposition: 26/12/2024
Map released: 21/05/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: tetrameric ion channel TrpA1
Fitted models: 9moe

Deposition Authors: Nie S
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318.
Broad LM, Suico JG, Turner PK, Nie S, Johnson KW , Sanger HE, Wegiel LA, Sperry DC, Remick D, Moran M, Malekiani S, Del Camino D, Wu X, Chong JA, Blair NT, Wilke AV
(2025) Pain , 166 , 1893 - 1908
PUBMED: 40258136
DOI: doi:10.1097/j.pain.0000000000003570
ISSN: 1872-6623
Grant Support: