EMD-48452

Single-particle
5.6 Å
EMD-48452
3D View Gallery
Deposition: 25/12/2024
Map released: 28/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48452

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mo9 summary report (pdf.gz) Map-9mo9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free rotated state (lower strand)

EMD-48452

Single-particle
5.6 Å
EMD-48452
3D View Gallery
Deposition: 25/12/2024
Map released: 28/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Native murine cardiac thin filament variant I79N in troponin T at pCa=5.8
Fitted models: 9mo9

Deposition Authors: Risi CM, Galkin VE
The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn.
Risi CM, Landim-Vieira M , Belknap B, Chase PB, Pinto JR , Galkin VE
(2025) J.Mol.Cell.Cardiol. , 204 , 55 - 67
PUBMED: 40412797
DOI: doi:10.1016/j.yjmcc.2025.05.005
ISSN: 1095-8584