EMD-48443

Single-particle
2.78 Å
EMD-48443
3D View Gallery
Deposition: 24/12/2024
Map released: 05/03/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48443

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mny summary report (pdf.gz) Map-9mny FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human MPC with pyruvate

EMD-48443

Single-particle
2.78 Å
EMD-48443
3D View Gallery
Deposition: 24/12/2024
Map released: 05/03/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, synthetic construct, Escherichia coli
Sample: Human MPC with pyruvate
Fitted models: 9mny

Deposition Authors: Zhang J , He Z, Feng L
Structure of mitochondrial pyruvate carrier and its inhibition mechanism.
He Z, Zhang J , Xu Y, Fine EJ , Suomivuori CM , Dror RO , Feng L
(2025) Nature , 641 , 250 - 257
PUBMED: 40044865
DOI: doi:10.1038/s41586-025-08667-y
ISSN: 1476-4687
ASTM: NATUAS