EMD-48331

Single-particle
3.4 Å
EMD-48331
3D View Gallery
Deposition: 17/12/2024
Map released: 29/10/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48331

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mkn summary report (pdf.gz) Map-9mkn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the Respiratory Syncytial Virus Fusion Protein Bound to Human Antibodies RSV_2245 and RSV_3301

EMD-48331

Single-particle
3.4 Å
EMD-48331
3D View Gallery
Deposition: 17/12/2024
Map released: 29/10/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Respiratory syncytial virus
Sample: Complex of trimeric fusion protein bound 1:1 to 2245 Fab VH/VL and 3301 Fab VH/VL
Fitted models: 9mkn

Deposition Authors: Johnson NV, McLellan JS
Generation of antigen-specific paired-chain antibodies using large language models.
Wasdin PT, Johnson NV, Janke AK, Held S , Marinov TM, Jordaan G, Gillespie RA, Vandenabeele L, Pantouli F, Powers OC, Vukovich MJ, Holt CM, Kim J, Hansman G, Logue J, Chu HY, Andrews SF, Kanekiyo M, Sautto GA, Ross TM, Sheward DJ, McLellan JS, Abu-Shmais AA, Georgiev IS
(2025) Cell , 188 , 7206
PUBMED: 41192421
DOI: doi:10.1016/j.cell.2025.10.006
ISSN: 1097-4172
Grant Support: